A 44-year-old male smoker with a history of scalp melanoma presents with an incidental 1.4 x 1.1 cm pulmonary nodule in the right middle lobe.
He underwent bronchoscopy with electromagnetic navigation bronchoscopy, FNA and TBBX of the RML nodule,
The smears and cell block reveal discohesive, pleomorphic tumor cells. An immunohistochemical panel was performed, and the tumor cells were positive for SOX-10, Mart-1, and S100, while negative for CK7, CK20, TTF-1, Napsin A, and p40.
FNA Interpretation: Malignant cells present, consistent with melanoma